PRKACA CLIA Kit for Bovine(Bos taurus) | EIAab.comPRKACA CLIA Kit for Bovine(Bos taurus)

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Index > Protein center > PRKACA(Gene name) > Bovine

PRKACA (Gene name),

cAMP-dependent protein kinase catalytic subunit alpha (Protein name ), KAPCA_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PRKACA;

Protein name:

cAMP-dependent protein kinase catalytic subunit alpha(PKA C-alpha);

Alternative:

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.

Function:

Phosphorylates a large number of substrates in the cytoplasm and the nucleus.

Subcellular Location:

Cytoplasm Nucleus Translocates into the nucleus (monomeric catalytic subunit). The inactive holoenzyme is found in the cytoplasm.

Protein Attributes:

Sequence length:

351

Sequence:

50:

100:

150:

200:

250:

300:

350:

351:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P00517

UniGene:

Bt.4420

String:

P00517

KEGG:

bta:282322

Pfam:

PF00069

STRING:

9913.ENSBTAP00000008727

Uniprot:

P00517

FOR

ELISA Kit for Bovine PKA C-alpha

Cat.:

E1918h

Price:

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Manual:

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Packing:

96T

Range:

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ELISA Kit for Bovine PKA C-alpha

Cat.:

E1918m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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ELISA Kit for Bovine PKA C-alpha

Cat.:

E1918r

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Manual:

Looking for manual.

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Packing:

96T

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ELISA Kit for Bovine PKA C-alpha

Cat.:

E1918d

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Bovine PKA C-alpha

Cat.:

E1918p

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Bovine PKA C-alpha

Cat.:

E1918b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Bovine PKA C-alpha

Cat.:

U1918m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Bovine PKA C-alpha

Cat.:

U1918r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Bovine PKA C-alpha

Cat.:

U1918b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Bovine PKA C-alpha

Cat.:

U1918d

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine PKA C-alpha

Cat.:

U1918p

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine PKA C-alpha

Cat.:

U1918h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Bovine PKA C-alpha

Cat.:

P1918Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine PKA C-alpha

Cat.:

P1918Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine PKA C-alpha

Cat.:

P1918Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Bovine PKA C-alpha

Protein for Bovine PKA C-alpha

Cat.:

R1918h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Bovine PKA C-alpha

Cat.:

R1918m

Price:

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Packing:

1mg

Purity:

>90%

Protein for Bovine PKA C-alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning of the C alpha catalytic subunit of the bovine cAMP-dependent protein kinase."
Wiemann S. , Kinzel V. , Pyerin W.
Biochim. Biophys. Acta1171:93-96(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Heart.
2.

"Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase."
Shoji S. , Parmelee D.C. , Wade R.D. , Kumar S. , Ericsson L.H. , Walsh K.A. , Neurath H. , Lonh G.L. , Demaille J.G. , Fischer E.H. , Titani K.
Proc. Natl. Acad. Sci. U.S.A.78:848-851(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-351;MYRISTOYLATION AT GLY-2;PHOSPHORYLATION AT THR-198 AND SER-339
3.

"Amino acid sequence of the catalytic subunit of bovine type II adenosine cyclic 3',5'-phosphate dependent protein kinase."
Shoji S. , Ericsson L.H. , Walsh K.A. , Fischer E.H. , Titani K.
Biochemistry22:3702-3709(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-351
4.

"Modification of the catalytic subunit of bovine heart cAMP-dependent protein kinase with affinity labels related to peptide substrates."
Bramson H.N. , Thomas N. , Matsueda R. , Nelson N.C. , Taylor S.S. , Kaiser E.T.
J. Biol. Chem.257:10575-10581(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 196-214;ACTIVE SITE
5.

"A conserved deamidation site at Asn 2 in the catalytic subunit of mammalian cAMP-dependent protein kinase detected by capillary LC-MS and tandem mass spectrometry."
Jedrzejewski P.T. , Girod A. , Tholey A. , Koenig N. , Thullner S. , Kinzel V. , Bossemeyer D.
Protein Sci.7:457-469(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-8;MUTAGENESIS OF ASN-3;DEAMIDATION AT ASN-3
6.

"Intracellular distribution of mammalian protein kinase A catalytic subunit altered by conserved Asn2 deamidation."
Pepperkok R. , Hotz-Wagenblatt A. , Koenig N. , Girod A. , Bossemeyer D. , Kinzel V.
J. Cell Biol.148:715-726(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEAMIDATION AT ASN-3;SUBCELLULAR LOCATION
7.

"The amino terminus of PKA catalytic subunit- a site for introduction of posttranslational heterogeneities by deamidation: D-Asp2 and D-isoAsp2 containing isozymes."
Kinzel V. , Koenig N. , Pipkorn R. , Bossemeyer D. , Lehmann W.D.
Protein Sci.9:2269-2277(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEAMIDATION AT ASN-3;CHARACTERIZATION OF ASP-3 ISOMERS
8.

"Rab13 regulates PKA signaling during tight junction assembly."
Koehler K. , Louvard D. , Zahraoui A.
J. Cell Biol.165:175-180(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RAB13
9.

"Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity."
Engh R.A. , Girod A. , Kinzel V. , Huber R. , Bossemeyer D.
J. Biol. Chem.271:26157-26164(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)
10.

"Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential."
Prade L. , Engh R.A. , Girod A. , Kinzel V. , Huber R. , Bossemeyer D.
Structure5:1627-1637(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS)

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